{"id":11529,"date":"2025-12-17T20:28:44","date_gmt":"2025-12-17T20:28:44","guid":{"rendered":"https:\/\/www.merck.ca\/en\/?page_id=11529"},"modified":"2026-10-16T14:46:40","modified_gmt":"2026-10-16T14:46:40","slug":"cardio-metabolic-disorders","status":"publish","type":"page","link":"https:\/\/www.merck.ca\/en\/research-and-products\/cardio-metabolic-disorders\/","title":{"rendered":"Cardio-metabolic disorders"},"content":{"rendered":"\n<div id=\"mco-b2-hero-block-block_c2a506eabded365c9fff32b64b452acf\" class=\"mco-b2-hero-block full mccberg-block\">\n    <div class=\"mco-b2-hero-block-wrapper\">\n        <div class=\"mco-b2-hero-block-image-section \">\n                            <div class=\"mco-b2-hero-block-image-container \">\n                    <picture >\n\t<source media=\"(max-width: 767px)\" data-srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=768&#038;quality=70&#038;allow_lossy=1\" srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=768&#038;quality=70&#038;allow_lossy=1\" >\n<source media=\"(min-width: 768px) and (max-width: 1199px)\" data-srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?h=768&#038;quality=80&#038;allow_lossy=1\" srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?h=768&#038;quality=80&#038;allow_lossy=1\" >\n<source media=\"(min-width: 1200px) and (max-width: 1919px)\" data-srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=1200&#038;quality=80&#038;allow_lossy=1\" srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=1200&#038;quality=80&#038;allow_lossy=1\" >\n<source media=\"(min-width: 1920px)\" data-srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=1920&#038;quality=80&#038;allow_lossy=1\" srcset=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=1920&#038;quality=80&#038;allow_lossy=1\" >\n\t<img data-src=\"https:\/\/www.merck.ca\/en\/wp-content\/uploads\/sites\/20\/2021\/11\/Cardio-Metabolic-Disorders-banner.jpeg?w=1920&#038;quality=80&#038;allow_lossy=1\" alt=\"Cardio-Metabolic-Disorders-banner\" class=\"eager \" loading=\"eager\" \/>\n<\/picture>                                    <\/div>\n                        <div class=\"mco-b2-hero-block-image-container-two\">\n                            <\/div>\n        <\/div>\n\n        <div class=\"mco-b2-hero-block-content-section\">\n            <nav class=\"breadcrumbs wrapper text-descriptive\"aria-label=\"Breadcrumbs\"><\/nav>            \n                            <h1 class=\"custom-heading block fixed-h1\"   >Cardio-metabolic disorders<\/h1>            \n                            <div class=\"mco-b2-hero-block-description\"><p>We have a long history of making an impact in cardio-metabolic disorders, such as type 2 diabetes and cardiovascular disease.<\/p>\n<\/div>\n            \n                    <\/div>\n    <\/div>\n\n    \n<\/div>\n\n\n<div id=\"mco-title-block-block_c7edbe86fa23ee19b8986c46f53f799a\"\n\t class=\"mco-title-block mccberg-block aligncenter\"\n\t >\n\t<div class=\"wrapper\">\n\t\t<div class=\"mco-title-block-content\">\n\t\t\t\n\t\t\t<h2 class=\"custom-heading block mco-title-block-title fixed-h2\"   >Our focus on cardio-metabolic disorders research<\/h2>\t\t\t\t\t\t\t<p class=\"mco-title-block-description\"><p style=\"text-align: center\">We continue our efforts to deeply understand cardio-metabolic disorders. Cardio-metabolic disorders include cardiovascular diseases, such as heart failure and pulmonary arterial hypertension (PAH), and metabolic diseases, such as type 2 diabetes. They represent some of the most serious health challenges of the 21st century.<\/p>\n<p style=\"text-align: center\">Advancements in cardio-metabolic research can make an impactful difference for patients, and there\u2019s still much more work to be done. We strive for scientific excellence and innovation in all stages of research, from discovery through approval and afterwards.<\/p>\n<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"mco-title-block-block_e8db4c267f666f895b55871f4c3110c7\"\n\t class=\"mco-title-block mccberg-block pull-up-stats negative mb-2 aligncenter\"\n\t >\n\t<div class=\"wrapper\">\n\t\t<div class=\"mco-title-block-content\">\n\t\t\t\n\t\t\t<h2 class=\"custom-heading block mco-title-block-title fixed-h2\"   >The impact of cardio-metabolic disorders<\/h2>\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<div class=\"wp-block-group has-small-font-size\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:14px\"><strong>Cardiovascular disease<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color wp-elements-5fb0dc7ba977d06607fe9347d3a3eafc wp-block-paragraph\" style=\"color:#00857c;font-size:40px\">~86,000<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:12px\">deaths in Canada from heart disease or stroke<sup>1<\/sup><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:14px\"><strong><strong>Diabetes<\/strong><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color wp-elements-3f318d88edc09f79c1f29ee0cf9d8555 wp-block-paragraph\" style=\"color:#00857c;font-size:40px\">7.3M<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:12px\">Canadians predicted to have diabetes by 2034<sup>2<\/sup><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:14px\"><strong><strong>Type 2 diabetes<\/strong><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color wp-elements-75141bf1651a79b8f465bf17a536d446 wp-block-paragraph\" style=\"color:#00857c;font-size:40px\">~90%<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:12px\">Percentage of diabetes cases in Canada that are Type 2<sup>3<\/sup><\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:14px\"><strong><strong>Pulmonary arterial hypertension (PAH)<\/strong><\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color wp-elements-8fe20ff3001cf2f39f865f300013bb87 wp-block-paragraph\" style=\"color:#00857c;font-size:40px\">2,000 to 4,000<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\" style=\"font-size:12px\">Canadians are affected by PAH, a rare disease that impacts the lungs and heart<sup>4<\/sup><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:40%\"><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<style>\ndiv#mco-title-block-block_e8db4c267f666f895b55871f4c3110c7 {\n    padding-bottom: 0px !important;\n}\n\n<\/style>\n\n\n\n<div class=\"wp-block-columns border-top-1 is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<h3 class=\"wp-block-heading\">Cardiovascular disease<\/h3>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p class=\"wp-block-paragraph\">We continue to build on our history in cardiovascular disease to help increase our understanding and help patients around the world.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We work with experts throughout the cardiovascular community to advance research that can help improve the lives of patients with cardiovascular disease.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns border-top-1 is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<h3 class=\"wp-block-heading\">Diabetes<\/h3>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p class=\"wp-block-paragraph\">We&#8217;re proud of our research team that is committed to helping people with type 2 diabetes.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns border-top-1 is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<h3 class=\"wp-block-heading\">Pulmonary arterial hypertension (PAH)<\/h3>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p class=\"wp-block-paragraph\">We&#8217;re focused on advancing research in the field of PAH, a rare, progressive and life-threatening blood vessel disorder in which the pulmonary arteries (blood vessels that carry blood from the right side of the heart into the lungs) become thickened and narrowed. As a result, the right side of the heart needs to work harder to pump blood into the lungs. The extra effort eventually causes the heart muscle to become weak and fail.<sup>5<\/sup><a href=\"https:\/\/www.statcan.gc.ca\/o1\/en\/plus\/353-heart-and-stroke-month\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<hr class=\"wp-block-separator has-css-opacity is-style-default\"\/>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:12px\"><sup>1<\/sup> <a href=\"https:\/\/world-heart-federation.org\/world-heart-observatory\/countries\/canada\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.statcan.gc.ca\/o1\/en\/plus\/353-heart-and-stroke-month<\/a><br><sup>2<\/sup> <a href=\"https:\/\/www.diabetes.ca\/what-is-diabetes\/diabetes-in-canada\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.diabetes.ca\/DiabetesCanadaWebsite\/ media\/Advocacy-and-Policy\/Backgrounder\/ 2020_Backgrounder_Canada_English_FINAL.pdf<\/a><br><sup>3<\/sup> <a href=\"https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/diabetes.html\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/type-2-diabetes.html<\/a><br><sup>4<\/sup> <a href=\"https:\/\/www.canada.ca\/content\/dam\/pmprb-cepmb\/documents\/consultations\/scoping-paper\/submissions\/Scoping%20paper%202023_Written%20submission_Pulmonary%20Hypertension%20Association%20of%20Canada_PHA_EN.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.phacanada.ca\/about-ph<\/a><br><sup>5<\/sup> <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/pulmonary-hypertension\/symptoms-causes\/syc-20350697\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.mayoclinic.org\/diseases-conditions\/pulmonary-hypertension\/symptoms-causes\/syc-20350697<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:12px\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cardiovascular disease ~86,000 deaths in Canada from heart disease or stroke1 Diabetes 7.3M Canadians predicted to have diabetes by 20342 Type 2 diabetes ~90% Percentage of diabetes cases in Canada that are Type 23 Pulmonary arterial hypertension (PAH) 2,000 to 4,000 Canadians are affected by PAH, a rare disease that impacts the lungs and heart4 [&hellip;]<\/p>\n","protected":false},"author":1049,"featured_media":11530,"parent":3909,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"editor_notices":[],"footnotes":""},"class_list":["post-11529","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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